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中國(guó)藥科大學(xué)是一所歷史悠久、特色鮮明、學(xué)風(fēng)優(yōu)良、在藥學(xué)界享有盛譽(yù)的教育部直屬、國(guó)家“雙一流”建設(shè)高校（一流學(xué)科），是我國(guó)首批具有博士、碩士學(xué)位授予權(quán)的高等學(xué)校之一，擁有一流藥學(xué)、中藥學(xué)類相關(guān)專業(yè)和創(chuàng)新平臺(tái)，具備完備的藥學(xué)、中藥學(xué)學(xué)科體系。（http://www.cpu.edu.cn）。

china pharmaceutical university is a prestigious institution with a long history, distinctive features, and excellent academic atmosphere. it is directly affiliated with the ministry of education as one of the national double first-class universities (first-class discipline). it is among the first batch of higher education institutions in china authorized to grant doctoral and master's degrees. the university offers solid pharmacy and traditional chinese medicine-related programs, along with various innovation platforms. additionally, it offers a well-rounded and diverse curriculum that covers both pharmacy and traditional chinese medicine disciplines. please visit the official websitehttp://www.cpu.edu.cnfor more details.

一、課題組介紹

合作導(dǎo)師何牟欣亞，中國(guó)藥科大學(xué)教授，博士生導(dǎo)師，入選國(guó)家高層次人才計(jì)劃。2014年于新加坡南洋理工大學(xué)獲得博士學(xué)位并從事博士后研究，2022年8月加入中國(guó)藥科大學(xué)中藥學(xué)院。以第一作者（或者共同第一作者）在jacs, pnas, acs catalysis，new phytologist，organic letters等國(guó)際知名期刊發(fā)表多篇研究論文，申請(qǐng)國(guó)際和國(guó)內(nèi)發(fā)明專利2項(xiàng)。擔(dān)任frontiers in nutrition, molecules等學(xué)術(shù)期刊特邀編委。

課題組主要從事穩(wěn)定多肽藥物設(shè)計(jì)與合成研究。天然穩(wěn)定多肽是一類尚未充分挖掘的可成藥活性分子，具有高穩(wěn)定性，高生物利用度，是生物藥的優(yōu)秀先導(dǎo)體。然其機(jī)理研究和成藥性受到天然低表達(dá)量的局限，因此對(duì)其合成途徑的解析和人工合成的技術(shù)研發(fā)是以天然穩(wěn)定多肽為基礎(chǔ)進(jìn)行新藥研發(fā)的關(guān)鍵。

課題組的主要研究方向?yàn)椋?/p>

1)天然多肽合成酶的系統(tǒng)性挖掘、設(shè)計(jì)改造及藥物合成應(yīng)用

2)穩(wěn)定活性多肽的化學(xué)合成技術(shù)研發(fā)

3)基于穩(wěn)定多肽骨架的多肽藥物設(shè)計(jì)、虛擬篩選及活性驗(yàn)證

因課題組發(fā)展需要，現(xiàn)公開招聘博士后2名，長(zhǎng)期有效。課題組保障待遇并全力支持博士后的科研發(fā)展，誠(chéng)邀海內(nèi)外英才加入。

the group leader is professor xinya hemu, recipient of china pharmaceutical university’s high-level talent introduction program, ncsf distinguished overseas young talent. she received her ph.d. from nanyang technological university, singapore, in 2014 and pursued postdoctoral research before joining the school of traditional chinese medicine at china pharmaceutical university in august 2022. as the first author (or co-first author), she has published numerous research articles in internationally renowned journals such as jacs, pnas, acs catalysis, new phytologist, and organic letters, and has applied for two international and domestic patents. she is also an invited editor for academic journals such as frontiers in nutrition and molecules.

hemu’s research group primarily focuses on the design and synthesis of stable peptide drugs. natural stable peptides are a class of underexplored drug-like active molecules with high stability and high bioavailability, making them excellent precursors for biopharmaceuticals. however, their mechanistic research and druggability are limited by their low natural expression levels. therefore, the analysis of their synthetic pathways and the development of artificial synthesis techniques are critical for new drug development based on natural stable peptides.

the main research areas include:

(1)systematic study of natural peptide synthetic enzymes on discovery, design, modification, and application on drug synthesis

(2)development of chemical synthesis technology for stable active peptides

(3)peptide drug design based on stable peptide scaffolds, virtual screening, and functional validation

two post-doctoral positions are open for application with no immediate closing date. the research group guarantees compensation, and fully supports the scientific research development of postdoctoral researchers.

二、招聘崗位

崗位1：已經(jīng)或即將獲得生物信息學(xué)、計(jì)算生物學(xué)、結(jié)構(gòu)生物學(xué)等相關(guān)專業(yè)的博士學(xué)位并有長(zhǎng)遠(yuǎn)科研事業(yè)規(guī)劃的申請(qǐng)人，優(yōu)先考慮具有酶學(xué)相關(guān)研究背景的候選人。

工作內(nèi)容：

1.蛋白結(jié)構(gòu)/動(dòng)力學(xué)/量子力學(xué)計(jì)算、功能-結(jié)構(gòu)關(guān)系圖譜的機(jī)器學(xué)習(xí)模型構(gòu)建、藥物虛擬篩選平臺(tái)構(gòu)建等相關(guān)科研工作；

2.協(xié)助進(jìn)行項(xiàng)目申請(qǐng)和管理；

3.協(xié)助指導(dǎo)研究生的科研工作

崗位2：已經(jīng)或即將獲得生物學(xué)或藥學(xué)等相關(guān)專業(yè)的博士學(xué)位并有長(zhǎng)遠(yuǎn)科研事業(yè)規(guī)劃的申請(qǐng)人，優(yōu)先考慮具有細(xì)胞生物學(xué)、實(shí)驗(yàn)動(dòng)物學(xué)、電生理學(xué)背景的博士。

工作內(nèi)容：

1.先導(dǎo)藥物的體內(nèi)外活性檢測(cè)平臺(tái)搭建，藥理分析等相關(guān)科研工作；

2.協(xié)助進(jìn)行項(xiàng)目申請(qǐng)和管理；

3.協(xié)助指導(dǎo)研究生的科研工作

應(yīng)聘條件：

（1）以第一作者身份在sci雜志上發(fā)表論文或者已經(jīng)接收；

（2）具有專業(yè)的寫作和閱讀能力，能夠積極追蹤所研究方向的前沿論文，可獨(dú)立完成sci論文的寫作；

（3）具備良好溝通和執(zhí)行能力，可在指導(dǎo)下獨(dú)立開展課題研究和項(xiàng)目管理；

（4）熱愛(ài)科研、積極樂(lè)觀、有很強(qiáng)的責(zé)任心和團(tuán)隊(duì)合作意識(shí)，有堅(jiān)定的學(xué)術(shù)追求。

position #1: phd students who are nearing the completion of or have recently completed their studies in bioinformatics / computational biology / structural biology and are considering a postdoctoral position as the next stage in their career development. priority will be given to candidates with a research background in enzymology.

responsibilities:

1.research work related to protein structure, md, qm/mm, machine learning model construction for structure-function relationship atlas, development of virtual screening platform;

2.assist in grant application and management;

3.guide graduate students in their research work.

position #2: phd students who are nearing the completion of or have recently completed their studies in biology / pharmacology and are considering a postdoctoral position as the next stage in their career development. priority will be given to candidates with a research background in cell biology, experimental animal science, and electrophysiology.

responsibilities:

1.research works related to the establishment of in vitro and in vivo activity testing platforms for lead drugs, as well as pharmacological analysis;

2.assist in grant application and management;

3.guide graduate students in their research work.

requirements:

1.have published articles(or with the acceptance letter) as the first author in peer-reviewed sci journals;

2.professional writing and reading skills, able to actively track recent research papers in the field, and independently complete sci article writing;

3.strong communication and execution skills, capable of conducting research independently and managing project under guidance;

4.passionate about scientific research, positive and optimistic, with a strong sense of responsibility and team collaboration, with a determined pursuit of academic excellence.

三、崗位待遇

1、根據(jù)個(gè)人情況，聘為興藥科研博士后（年薪約29萬(wàn)）。同時(shí)博士后人員在站期間，享受公費(fèi)醫(yī)療、公積金以及校工會(huì)有關(guān)待遇。在教學(xué)和科研方面取得突出成果，可享受學(xué)校相應(yīng)的獎(jiǎng)勵(lì)政策。出站后，可申報(bào)具有正式編制的講師或副研究員。具體要求及待遇詳情請(qǐng)參見《中國(guó)藥科大學(xué)博士后工作管理辦法（試行）》https://rsc.cpu.edu.cn/67/83/c4819a157571/page.htm。

2、課題組協(xié)助申報(bào)國(guó)家、省部級(jí)課題及相關(guān)機(jī)構(gòu)提供的博士后資助（如江蘇省卓越博士后計(jì)劃（15萬(wàn)/年）等）。

benefits

the shortlisted candidate will be appointed as a postdoctoral researcher in pharmaceutical sciences with an annual salary of approximately 280,000 rmb. during the postdoctoral period, the researcher will enjoy employee benefits (public medical insurance, housing provident fund, and benefits related to the university labor union). those who achieve outstanding results in teaching and research can enjoy the corresponding reward policies of the university. after completing the postdoctoral position, candidates can apply for a formal lecturer or associate researcher position. for specific requirements and compensation details, please refer to“china pharmaceutical university postdoctoral work management measures (trial implementation)”https://rsc.cpu.edu.cn/67/83/c4819a157571/page.htm.

the research group will assist in applying for national, provincial, and ministerial-level projects, as well as postdoctoral funding provided by relevant organizations (e.g. outstanding postdoctoral program of jiangsu province (150,000 rmb/year) ).

四、申請(qǐng)材料documents for application

·個(gè)人簡(jiǎn)歷及相關(guān)支持材料resume and supporting documents

·代表性科研成果representative research achievements

·求職信（簡(jiǎn)述科研興趣和發(fā)展規(guī)劃）cover letter (briefly introduce your research interests and future plan)

·3封推薦信（由推薦人直接發(fā)送至聯(lián)系人郵箱）three recommendation letters (to be sent directly by the recommender to the contact’s email)

五、應(yīng)聘方式

請(qǐng)應(yīng)聘者將申請(qǐng)材料通過(guò)電子郵件發(fā)送至hemuxinya@cpu.edu.cn（何老師）。郵件標(biāo)題請(qǐng)注明：“應(yīng)聘博士后+姓名+今日招聘網(wǎng)jrzp.com”字樣。應(yīng)聘材料將予以嚴(yán)格保密。經(jīng)初步審核通過(guò)者，課題組將盡快安排面試。

how to apply

interested applicants should send their application materials (except the recommendation letters) via email tohemuxinya@cpu.edu.cn(dr. hemu). please indicate postdoc application + your name in the email subject line. all application materials will be treated with strict confidentiality. after an initial review, the research group will arrange interviews for qualified candidates as soon as possible.

信息來(lái)源于網(wǎng)絡(luò)，如有變更請(qǐng)以原發(fā)布者為準(zhǔn)。

來(lái)源鏈接：

http://rsc.cpu.edu.cn/c5/89/c4809a181641/page.htm

更多最新博士后招收資訊請(qǐng)關(guān)注高才博士后微信公眾號(hào)（微信號(hào)：bshjob）。

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